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Insight into glucocorticoid receptor signalling through interactome model analysis

Glucocorticoid hormones (GCs) are used to treat a variety of diseases because of their potent anti-inflammatory effect and their ability to induce apoptosis in lymphoid malignancies through the glucocorticoid receptor (GR). Despite ongoing research, high glucocorticoid efficacy and widespread usage...

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Detalles Bibliográficos
Autores principales: Bakker, Emyr, Tian, Kun, Mutti, Luciano, Demonacos, Constantinos, Schwartz, Jean-Marc, Krstic-Demonacos, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690696/
https://www.ncbi.nlm.nih.gov/pubmed/29107989
http://dx.doi.org/10.1371/journal.pcbi.1005825