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Base pair probability estimates improve the prediction accuracy of RNA non-canonical base pairs

Prediction of RNA tertiary structure from sequence is an important problem, but generating accurate structure models for even short sequences remains difficult. Predictions of RNA tertiary structure tend to be least accurate in loop regions, where non-canonical pairs are important for determining th...

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Detalles Bibliográficos
Autores principales: Sloma, Michael F., Mathews, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690697/
https://www.ncbi.nlm.nih.gov/pubmed/29107980
http://dx.doi.org/10.1371/journal.pcbi.1005827