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Directing leukocyte polarization and migration by the phosphoinositide transfer protein TIPE2

Leukocyte polarization toward chemoattractants is essential for directed leukocyte migration, or chemotaxis. How leukocytes acquire polarity upon encountering chemical gradients is not well understood. We report here that leukocyte polarity is generated by TIPE2 (TNFAIP8L2), a transfer protein of ph...

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Detalles Bibliográficos
Autores principales: Fayngerts, Svetlana A., Wang, Zhaojun, Zamani, Ali, Sun, Honghong, Boggs, Amanda E., Porturas, Thomas P., Xie, Weidong, Lin, Mei, Cathopoulis, Terry, Goldsmith, Jason R., Vourekas, Anastassios, Chen, Youhai H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690821/
https://www.ncbi.nlm.nih.gov/pubmed/29058702
http://dx.doi.org/10.1038/ni.3866