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Directing leukocyte polarization and migration by the phosphoinositide transfer protein TIPE2
Leukocyte polarization toward chemoattractants is essential for directed leukocyte migration, or chemotaxis. How leukocytes acquire polarity upon encountering chemical gradients is not well understood. We report here that leukocyte polarity is generated by TIPE2 (TNFAIP8L2), a transfer protein of ph...
Autores principales: | Fayngerts, Svetlana A., Wang, Zhaojun, Zamani, Ali, Sun, Honghong, Boggs, Amanda E., Porturas, Thomas P., Xie, Weidong, Lin, Mei, Cathopoulis, Terry, Goldsmith, Jason R., Vourekas, Anastassios, Chen, Youhai H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690821/ https://www.ncbi.nlm.nih.gov/pubmed/29058702 http://dx.doi.org/10.1038/ni.3866 |
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