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A muscle specific protein “myoferlin” modulates IL-6/STAT3 signaling by chaperoning activated STAT3 to nucleus

Myoferlin, a member of ferlin family of proteins, was first discovered as a candidate gene for muscular dystrophy and cardiomyopathy. Recently myoferlin was shown to be also expressed in endothelial and cancer cells where it was shown to modulate VEGFR-2 and EGFR signaling by enhancing their stabili...

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Detalles Bibliográficos
Autores principales: Yadav, Arti, Kumar, Bhavna, Lang, James C., Teknos, Theodoros N, Kumar, Pawan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690845/
https://www.ncbi.nlm.nih.gov/pubmed/28745314
http://dx.doi.org/10.1038/onc.2017.245