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Osteopontin is linked with AKT, FoxO1, and myostatin in skeletal muscle cells

Introduction: Osteopontin (OPN) polymorphisms are associated with muscle size and modify disease progression in Duchenne muscular dystrophy (DMD). We hypothesized that OPN may share a molecular network with myostatin (MSTN). Methods: Studies were conducted in the golden retriever (GRMD) and mdx mous...

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Detalles Bibliográficos
Autores principales: Nghiem, Peter P., Kornegay, Joe N., Uaesoontrachoon, Kitipong, Bello, Luca, Yin, Ying, Kesari, Akanchha, Mittal, Priya, Schatzberg, Scott J., Many, Gina M., Lee, Norman H., Hoffman, Eric P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690863/
https://www.ncbi.nlm.nih.gov/pubmed/28745831
http://dx.doi.org/10.1002/mus.25752