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Elevation of p11 in lateral habenula mediates depression-like behavior

The lateral habenula (LHb) is a key brain region involved in the pathophysiology of depression. It is activated by stimuli associated with negative experiences and is involved in encoding aversive signals. Hyperactivity of LHb is found in both rodent models of depression and human patients with depr...

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Detalles Bibliográficos
Autores principales: Seo, J-S, Zhong, P, Liu, A, Yan, Z, Greengard, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690885/
https://www.ncbi.nlm.nih.gov/pubmed/28507317
http://dx.doi.org/10.1038/mp.2017.96