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Elevation of p11 in lateral habenula mediates depression-like behavior
The lateral habenula (LHb) is a key brain region involved in the pathophysiology of depression. It is activated by stimuli associated with negative experiences and is involved in encoding aversive signals. Hyperactivity of LHb is found in both rodent models of depression and human patients with depr...
Autores principales: | Seo, J-S, Zhong, P, Liu, A, Yan, Z, Greengard, P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690885/ https://www.ncbi.nlm.nih.gov/pubmed/28507317 http://dx.doi.org/10.1038/mp.2017.96 |
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