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Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25

The Plasmodium falciparum Pfs25 protein (Pfs25) is a leading malaria transmission-blocking vaccine antigen. Pfs25 vaccination is intended to elicit antibodies that inhibit parasite development when ingested by Anopheles mosquitoes during blood meals. The Pfs25 three-dimensional structure has remaine...

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Detalles Bibliográficos
Autores principales: Scally, Stephen W., McLeod, Brandon, Bosch, Alexandre, Miura, Kazutoyo, Liang, Qi, Carroll, Sean, Reponen, Sini, Nguyen, Ngan, Giladi, Eldar, Rämisch, Sebastian, Yusibov, Vidadi, Bradley, Allan, Lemiale, Franck, Schief, William R., Emerling, Daniel, Kellam, Paul, King, C. Richter, Julien, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691035/
https://www.ncbi.nlm.nih.gov/pubmed/29146922
http://dx.doi.org/10.1038/s41467-017-01924-3