TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes

Lysosomal distribution is linked to the role of lysosomes in many cellular functions, including autophagosome degradation, cholesterol homeostasis, antigen presentation, and cell invasion. Alterations in lysosomal positioning contribute to different human pathologies, such as cancer, neurodegenerati...

Descripción completa

Detalles Bibliográficos
Autores principales: Willett, Rose, Martina, José A., Zewe, James P., Wills, Rachel, Hammond, Gerald R. V., Puertollano, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691037/
https://www.ncbi.nlm.nih.gov/pubmed/29146937
http://dx.doi.org/10.1038/s41467-017-01871-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691037/
https://www.ncbi.nlm.nih.gov/pubmed/29146937
http://dx.doi.org/10.1038/s41467-017-01871-z

Ejemplares similares