Wiskott-Aldrich syndrome protein regulates autophagy and inflammasome activity in innate immune cells

Dysregulation of autophagy and inflammasome activity contributes to the development of auto-inflammatory diseases. Emerging evidence highlights the importance of the actin cytoskeleton in modulating inflammatory responses. Here we show that deficiency of Wiskott–Aldrich syndrome protein (WASp), whic...

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Detalles Bibliográficos
Autores principales: Lee, Pamela P., Lobato-Márquez, Damián, Pramanik, Nayani, Sirianni, Andrea, Daza-Cajigal, Vanessa, Rivers, Elizabeth, Cavazza, Alessia, Bouma, Gerben, Moulding, Dale, Hultenby, Kjell, Westerberg, Lisa S., Hollinshead, Michael, Lau, Yu-Lung, Burns, Siobhan O., Mostowy, Serge, Bajaj-Elliott, Mona, Thrasher, Adrian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691069/
https://www.ncbi.nlm.nih.gov/pubmed/29146903
http://dx.doi.org/10.1038/s41467-017-01676-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691069/
https://www.ncbi.nlm.nih.gov/pubmed/29146903
http://dx.doi.org/10.1038/s41467-017-01676-0

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