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Single molecule multiplexed nanopore protein screening in human serum using aptamer modified DNA carriers

The capability to screen a range of proteins at the single-molecule level with enhanced selectivity in biological fluids has been in part a driving force in developing future diagnostic and therapeutic strategies. The combination of nanopore sensing and nucleic acid aptamer recognition comes close t...

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Detalles Bibliográficos
Autores principales: Sze, Jasmine Y. Y., Ivanov, Aleksandar P., Cass, Anthony E. G., Edel, Joshua B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691071/
https://www.ncbi.nlm.nih.gov/pubmed/29146902
http://dx.doi.org/10.1038/s41467-017-01584-3