Real-time wash-free detection of unlabeled PNA-DNA hybridization using discrete FET sensor

We demonstrate an electrochemical sensor for detection of unlabeled single-stranded DNA using peptide nucleic acid (PNA) probes coupled to the field-effect transistor (FET) gate. The label-free detection relies on the intrinsic charge of the DNA backbone. Similar detection schemes have mainly concen...

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Detalles Bibliográficos
Autores principales: Kaisti, Matti, Kerko, Anssi, Aarikka, Eero, Saviranta, Petri, Boeva, Zhanna, Soukka, Tero, Lehmusvuori, Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691077/
https://www.ncbi.nlm.nih.gov/pubmed/29147003
http://dx.doi.org/10.1038/s41598-017-16028-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691077/
https://www.ncbi.nlm.nih.gov/pubmed/29147003
http://dx.doi.org/10.1038/s41598-017-16028-7

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