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Expression profiling and immunolocalization of Na(+)-d-glucose-cotransporter 1 in mice employing knockout mice as specificity control indicate novel locations and differences between mice and rats

The expression and localization of sodium-d-glucose cotransporter SGLT1 (SLC5A1), which is involved in small intestinal glucose absorption and renal glucose reabsorption, is of high biomedical relevance because SGLT1 inhibitors are currently tested for antidiabetic therapy. In human and rat organs,...

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Detalles Bibliográficos
Autores principales: Madunić, Ivana Vrhovac, Breljak, Davorka, Karaica, Dean, Koepsell, Hermann, Sabolić, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691098/
https://www.ncbi.nlm.nih.gov/pubmed/28842746
http://dx.doi.org/10.1007/s00424-017-2056-1