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Expression profiling and immunolocalization of Na(+)-d-glucose-cotransporter 1 in mice employing knockout mice as specificity control indicate novel locations and differences between mice and rats
The expression and localization of sodium-d-glucose cotransporter SGLT1 (SLC5A1), which is involved in small intestinal glucose absorption and renal glucose reabsorption, is of high biomedical relevance because SGLT1 inhibitors are currently tested for antidiabetic therapy. In human and rat organs,...
Autores principales: | Madunić, Ivana Vrhovac, Breljak, Davorka, Karaica, Dean, Koepsell, Hermann, Sabolić, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691098/ https://www.ncbi.nlm.nih.gov/pubmed/28842746 http://dx.doi.org/10.1007/s00424-017-2056-1 |
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