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Effects of ageing on pro-arrhythmic ventricular phenotypes in incrementally paced murine Pgc-1β(−/−) hearts

A range of chronic clinical conditions accompany cardiomyocyte energetic dysfunction and constitute independent risk factors for cardiac arrhythmia. We investigated pro-arrhythmic and arrhythmic phenotypes in energetically deficient C57BL mice with genetic ablation of the mitochondrial promoter pero...

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Detalles Bibliográficos
Autores principales: Ahmad, Shiraz, Valli, Haseeb, Edling, Charlotte E., Grace, Andrew A., Jeevaratnam, Kamalan, Huang, Christopher L-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691113/
https://www.ncbi.nlm.nih.gov/pubmed/28821956
http://dx.doi.org/10.1007/s00424-017-2054-3