Excessive glucocorticoid-induced muscle MuRF1 overexpression is independent of Akt/FoXO1 pathway

The ubiquitin-proteasome system (UPS)-dependent proteolysis plays a major role in the muscle catabolic action of glucocorticoids (GCs). Atrogin-1 and muscle-specific RING finger protein 1 (MuRF1), two E3 ubiquitin ligases, are uniquely expressed in muscle. It has been previously demonstrated that GC...

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Detalles Bibliográficos
Autores principales: Wang, Xiao Juan, Xiao, Jing Jing, Liu, Lei, Jiao, Hong Chao, Lin, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691142/
https://www.ncbi.nlm.nih.gov/pubmed/29046370
http://dx.doi.org/10.1042/BSR20171056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691142/
https://www.ncbi.nlm.nih.gov/pubmed/29046370
http://dx.doi.org/10.1042/BSR20171056

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