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3D Spatially Resolved Models of the Intracellular Dynamics of the Hepatitis C Genome Replication Cycle

Mathematical models of virus dynamics have not previously acknowledged spatial resolution at the intracellular level despite substantial arguments that favor the consideration of intracellular spatial dependence. The replication of the hepatitis C virus (HCV) viral RNA (vRNA) occurs within special r...

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Detalles Bibliográficos
Autores principales: Knodel, Markus M., Reiter, Sebastian, Targett-Adams, Paul, Grillo, Alfio, Herrmann, Eva, Wittum, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691296/
https://www.ncbi.nlm.nih.gov/pubmed/28973992
http://dx.doi.org/10.3390/v9100282