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Engaging Ly‐6A/Sca‐1 triggers lipid raft‐dependent and ‐independent responses in CD4(+) T‐cell lines

INTRODUCTION: The lymphocyte antigen 6 (Ly‐6) supergene family encodes proteins of 12–14 kda in molecular mass that are either secreted or anchored to the plasma membrane through a glycosyl‐phosphatidylinisotol (GPI) lipid anchor at the carboxy‐terminus. The lipidated GPI‐anchor allows localization...

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Detalles Bibliográficos
Autores principales: Lang, Melissa A., Jenkins, Sultan A., Balzano, Phillip, Owoyele, Adeyinka, Patel, Akshay, Bamezai, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691314/
https://www.ncbi.nlm.nih.gov/pubmed/28660664
http://dx.doi.org/10.1002/iid3.182