LSD1, a double-edged sword, confers dynamic chromatin regulation but commonly promotes aberrant cell growth

Histone-modifying enzymes play a critical role in chromatin remodeling and are essential for influencing several genome processes such as gene expression and DNA repair, replication, and recombination. The discovery of lysine-specific demethylase 1 (LSD1), the first identified histone demethylase, d...

Descripción completa

Detalles Bibliográficos
Autores principales: Kozub, Meghan M, Carr, Ryan M, Lomberk, Gwen L, Fernandez-Zapico, Martin E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691370/
https://www.ncbi.nlm.nih.gov/pubmed/29225781
http://dx.doi.org/10.12688/f1000research.12169.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691370/
https://www.ncbi.nlm.nih.gov/pubmed/29225781
http://dx.doi.org/10.12688/f1000research.12169.1

Ejemplares similares