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Synthesis, characterization, cytotoxic screening, and density functional theory studies of new derivatives of quinazolin-4(3H)-one Schiff bases

A series of novel derivatives of quinazolinone Schiff bases were synthesized from benzoic acid starting material and evaluated for potential cytotoxic activities against the human breast adenocarcinoma (MCF-7) and the human colon adenocarcinoma (HT-29) cell lines. Compared to the reference drug, the...

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Detalles Bibliográficos
Autores principales: Nasab, Rezvan Rezaee, Hassanzadeh, Farshid, Khodarahmi, Ghadam Ali, Mirzaei, Mahmoud, Rostami, Mahboubeh, abadi, Ali Jahanian-Najaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691571/
https://www.ncbi.nlm.nih.gov/pubmed/29204173
http://dx.doi.org/10.4103/1735-5362.217425