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Live Attenuated Influenza Vaccine contains Substantial and Unexpected Amounts of Defective Viral Genomic RNA

The live attenuated influenza vaccine FluMist(®) was withdrawn in the USA by the Centers for Disease Control and Prevention after its failure to provide adequate protective immunity during 2013–2016. The vaccine uses attenuated core type A and type B viruses, reconfigured each year to express the tw...

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Detalles Bibliográficos
Autores principales: Gould, Philip S., Easton, Andrew J., Dimmock, Nigel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691621/
https://www.ncbi.nlm.nih.gov/pubmed/28934167
http://dx.doi.org/10.3390/v9100269