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Telomere Dynamics in Immune Senescence and Exhaustion Triggered by Chronic Viral Infection
The progressive loss of immunological memory during aging correlates with a reduced proliferative capacity and shortened telomeres of T cells. Growing evidence suggests that this phenotype is recapitulated during chronic viral infection. The antigenic volume imposed by persistent and latent viruses...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691640/ https://www.ncbi.nlm.nih.gov/pubmed/28981470 http://dx.doi.org/10.3390/v9100289 |