Polyprotein Processing as a Determinant for In Vitro Activity of Semliki Forest Virus Replicase

Semliki Forest virus (SFV) is an arthropod-borne alphavirus that induces membrane invaginations (spherules) in host cells. These harbor the viral replication complexes (RC) that synthesize viral RNA. Alphaviruses have four replicase or nonstructural proteins (nsPs), nsP1–4, expressed as polyprotein...

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Detalles Bibliográficos
Autores principales: Pietilä, Maija K., Albulescu, Irina C., van Hemert, Martijn J., Ahola, Tero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691643/
https://www.ncbi.nlm.nih.gov/pubmed/28991178
http://dx.doi.org/10.3390/v9100292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691643/
https://www.ncbi.nlm.nih.gov/pubmed/28991178
http://dx.doi.org/10.3390/v9100292

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