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Risk of respiratory depression with opioids and concomitant gabapentinoids

INTRODUCTION: The combination of opioids and central nervous system depressants such as benzodiazepines and barbiturates has an additive effect on the frequency of oversedation and respiratory depression requiring naloxone use in hospitalized patients. Gabapentinoids (gabapentin and pregabalin) are...

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Detalles Bibliográficos
Autores principales: Savelloni, Julie, Gunter, Heather, Lee, Kelly C, Hsu, Chih, Yi, Cassia, Edmonds, Kyle P, Furnish, Timothy, Atayee, Rabia S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691933/
https://www.ncbi.nlm.nih.gov/pubmed/29180889
http://dx.doi.org/10.2147/JPR.S144963