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Checkpoint blockade in solid tumors and B-cell malignancies, with special consideration of the role of CD200

In the ontogeny of a normal immune response, a series of checkpoints must be overcome to ensure that unwanted and/or harmful self-directed activation responses are avoided. Many of the molecules now known to be active in this overseeing of the evolving immune activation cascade, contributing inhibit...

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Detalles Bibliográficos
Autores principales: Gorczynski, Reginald M, Zhu, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5691938/
https://www.ncbi.nlm.nih.gov/pubmed/29180896
http://dx.doi.org/10.2147/CMAR.S147326