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Association of Tissue-Specific DNA Methylation Alterations with α-Thalassemia Southeast Asian Deletion

In the wild-type allele, DNA methylation levels of 10 consecutive CpG sites adjacent to the upstream 5′-breakpoint of α-thalassemia Southeast Asian (SEA) deletion are not different between placenta and leukocytes. However, no previous study has reported the map of DNA methylation in the SEA allele....

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Detalles Bibliográficos
Autores principales: Pangeson, Tanapat, Sanguansermsri, Phanchana, Sanguansermsri, Torpong, Seeratanachot, Teerapat, Suwanakhon, Narutchala, Srikummool, Metawee, Kaewkong, Worasak, Mahingsa, Khwanruedee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692129/
https://www.ncbi.nlm.nih.gov/pubmed/29162979
http://dx.doi.org/10.1177/1179237X17736107