Increased intracellular Ca(2+) concentrations prevent membrane localization of PH domains through the formation of Ca(2+)-phosphoinositides

Insulin resistance, a key etiological factor in metabolic syndrome, is closely linked to ectopic lipid accumulation and increased intracellular Ca(2+) concentrations in muscle and liver. However, the mechanism by which dysregulated intracellular Ca(2+) homeostasis causes insulin resistance remains e...

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Detalles Bibliográficos
Autores principales: Kang, Jin Ku, Kim, Ok-Hee, Hur, June, Yu, So Hee, Lamichhane, Santosh, Lee, Jin Wook, Ojha, Uttam, Hong, Jeong Hee, Lee, Cheol Soon, Cha, Ji-Young, Lee, Young Jae, Im, Seung-Soon, Park, Young Joo, Choi, Cheol Soo, Lee, Dae Ho, Lee, In-Kyu, Oh, Byung-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692539/
https://www.ncbi.nlm.nih.gov/pubmed/29078297
http://dx.doi.org/10.1073/pnas.1706489114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692539/
https://www.ncbi.nlm.nih.gov/pubmed/29078297
http://dx.doi.org/10.1073/pnas.1706489114

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