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Growth hormone-releasing hormone attenuates cardiac hypertrophy and improves heart function in pressure overload-induced heart failure

It has been shown that growth hormone-releasing hormone (GHRH) reduces cardiomyocyte (CM) apoptosis, prevents ischemia/reperfusion injury, and improves cardiac function in ischemic rat hearts. However, it is still not known whether GHRH would be beneficial for life-threatening pathological condition...

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Detalles Bibliográficos
Autores principales: Gesmundo, Iacopo, Miragoli, Michele, Carullo, Pierluigi, Trovato, Letizia, Larcher, Veronica, Di Pasquale, Elisa, Brancaccio, Mara, Mazzola, Marta, Villanova, Tania, Sorge, Matteo, Taliano, Marina, Gallo, Maria Pia, Alloatti, Giuseppe, Penna, Claudia, Hare, Joshua M., Ghigo, Ezio, Schally, Andrew V., Condorelli, Gianluigi, Granata, Riccarda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692579/
https://www.ncbi.nlm.nih.gov/pubmed/29078377
http://dx.doi.org/10.1073/pnas.1712612114