Small molecule Photoregulin3 prevents retinal degeneration in the Rho(P23H) mouse model of retinitis pigmentosa

Regulation of rod gene expression has emerged as a potential therapeutic strategy to treat retinal degenerative diseases like retinitis pigmentosa (RP). We previously reported on a small molecule modulator of the rod transcription factor Nr2e3, Photoregulin1 (PR1), that regulates the expression of p...

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Detalles Bibliográficos
Autores principales: Nakamura, Paul A, Shimchuk, Andy A, Tang, Shibing, Wang, Zhizhi, DeGolier, Kole, Ding, Sheng, Reh, Thomas A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693111/
https://www.ncbi.nlm.nih.gov/pubmed/29148976
http://dx.doi.org/10.7554/eLife.30577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693111/
https://www.ncbi.nlm.nih.gov/pubmed/29148976
http://dx.doi.org/10.7554/eLife.30577

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