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A minimally sufficient model for rib proximal-distal patterning based on genetic analysis and agent-based simulations
For decades, the mechanism of skeletal patterning along a proximal-distal axis has been an area of intense inquiry. Here, we examine the development of the ribs, simple structures that in most terrestrial vertebrates consist of two skeletal elements—a proximal bone and a distal cartilage portion. Wh...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693115/ https://www.ncbi.nlm.nih.gov/pubmed/29068314 http://dx.doi.org/10.7554/eLife.29144 |