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Investigating molecular crowding within nuclear pores using polarization-PALM

The key component of the nuclear pore complex (NPC) controlling permeability, selectivity, and the speed of nucleocytoplasmic transport is an assembly of natively unfolded polypeptides, which contain phenylalanine-glycine (FG) binding sites for nuclear transport receptors. The architecture and dynam...

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Detalles Bibliográficos
Autores principales: Fu, Guo, Tu, Li-Chun, Zilman, Anton, Musser, Siegfried M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693140/
https://www.ncbi.nlm.nih.gov/pubmed/28949296
http://dx.doi.org/10.7554/eLife.28716