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Investigating molecular crowding within nuclear pores using polarization-PALM
The key component of the nuclear pore complex (NPC) controlling permeability, selectivity, and the speed of nucleocytoplasmic transport is an assembly of natively unfolded polypeptides, which contain phenylalanine-glycine (FG) binding sites for nuclear transport receptors. The architecture and dynam...
Autores principales: | Fu, Guo, Tu, Li-Chun, Zilman, Anton, Musser, Siegfried M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693140/ https://www.ncbi.nlm.nih.gov/pubmed/28949296 http://dx.doi.org/10.7554/eLife.28716 |
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