Effect of a rare genetic variant of TM7SF4 gene on osteoclasts of patients with Paget’s disease of bone

BACKGROUND: Dendritic Cell-Specific Transmembrane Protein (DC-STAMP) is involved in osteoclastogenesis with a key role in mononucleated osteoclasts fusion. We reported in patients with Paget’s disease of bone (PDB) a rare variant (rs62620995) in the TM7SF4 gene, encoding for DC-STAMP, which changes...

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Detalles Bibliográficos
Autores principales: Laurier, Emilie, Amiable, Nathalie, Gagnon, Edith, Brown, Jacques P., Michou, Laëtitia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693359/
https://www.ncbi.nlm.nih.gov/pubmed/29145829
http://dx.doi.org/10.1186/s12881-017-0495-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693359/
https://www.ncbi.nlm.nih.gov/pubmed/29145829
http://dx.doi.org/10.1186/s12881-017-0495-3

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