The analysis of novel microRNA mimic sequences in cancer cells reveals lack of specificity in stem-loop RT-qPCR-based microRNA detection

OBJECTIVE: MicroRNAs are frequently downregulated in cancer, and restoring expression has tumour suppressive activity in tumour cells. Our recent phase I clinical trial investigated microRNA-based therapy in patients with malignant pleural mesothelioma. Treatment with TargomiRs, microRNA mimics with...

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Detalles Bibliográficos
Autores principales: Winata, Patrick, Williams, Marissa, McGowan, Eileen, Nassif, Najah, van Zandwijk, Nico, Reid, Glen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693513/
https://www.ncbi.nlm.nih.gov/pubmed/29149911
http://dx.doi.org/10.1186/s13104-017-2930-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693513/
https://www.ncbi.nlm.nih.gov/pubmed/29149911
http://dx.doi.org/10.1186/s13104-017-2930-0

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