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The analysis of novel microRNA mimic sequences in cancer cells reveals lack of specificity in stem-loop RT-qPCR-based microRNA detection

OBJECTIVE: MicroRNAs are frequently downregulated in cancer, and restoring expression has tumour suppressive activity in tumour cells. Our recent phase I clinical trial investigated microRNA-based therapy in patients with malignant pleural mesothelioma. Treatment with TargomiRs, microRNA mimics with...

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Detalles Bibliográficos
Autores principales:	Winata, Patrick, Williams, Marissa, McGowan, Eileen, Nassif, Najah, van Zandwijk, Nico, Reid, Glen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693513/ https://www.ncbi.nlm.nih.gov/pubmed/29149911 http://dx.doi.org/10.1186/s13104-017-2930-0

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