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Forebrain-specific, conditional silencing of Staufen2 alters synaptic plasticity, learning, and memory in rats

BACKGROUND: Dendritic messenger RNA (mRNA) localization and subsequent local translation in dendrites critically contributes to synaptic plasticity and learning and memory. Little is known, however, about the contribution of RNA-binding proteins (RBPs) to these processes in vivo. RESULTS: To delinea...

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Detalles Bibliográficos
Autores principales: Berger, Stefan M., Fernández-Lamo, Iván, Schönig, Kai, Fernández Moya, Sandra M., Ehses, Janina, Schieweck, Rico, Clementi, Stefano, Enkel, Thomas, Grothe, Sascha, von Bohlen und Halbach, Oliver, Segura, Inmaculada, Delgado-García, José María, Gruart, Agnès, Kiebler, Michael A., Bartsch, Dusan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693596/
https://www.ncbi.nlm.nih.gov/pubmed/29149906
http://dx.doi.org/10.1186/s13059-017-1350-8