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Role of microRNA-33a in regulating the expression of PD-1 in lung adenocarcinoma

BACKGROUND: MiRNAs are vital in functioning as either oncogenes or tumor suppressors in the cell cycle. Target transcripts for immune checkpoint molecules such as PD-1/PD-L1 and (programmed cell death-1/its ligand and cytotoxic T-lymphocyte antigen 4) have proven to be beneficial against several sol...

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Detalles Bibliográficos
Autores principales: Boldrini, Laura, Giordano, Mirella, Niccoli, Cristina, Melfi, Franca, Lucchi, Marco, Mussi, Alfredo, Fontanini, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693599/
https://www.ncbi.nlm.nih.gov/pubmed/29176936
http://dx.doi.org/10.1186/s12935-017-0474-y