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From IgG Fusion Proteins to Engineered-Specific Human Regulatory T Cells: A Life of Tolerance
Recent efforts have concentrated on approaches to expand and “specify” human regulatory T cells (Tregs) and to apply them to modulate adverse immune responses in autoimmunity and hemophilia. We have used retroviral transduction of specific T-cell receptor, single chain Fv, or antigen domains in Treg...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693857/ https://www.ncbi.nlm.nih.gov/pubmed/29181011 http://dx.doi.org/10.3389/fimmu.2017.01576 |