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From IgG Fusion Proteins to Engineered-Specific Human Regulatory T Cells: A Life of Tolerance

Recent efforts have concentrated on approaches to expand and “specify” human regulatory T cells (Tregs) and to apply them to modulate adverse immune responses in autoimmunity and hemophilia. We have used retroviral transduction of specific T-cell receptor, single chain Fv, or antigen domains in Treg...

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Detalles Bibliográficos
Autor principal: Scott, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693857/
https://www.ncbi.nlm.nih.gov/pubmed/29181011
http://dx.doi.org/10.3389/fimmu.2017.01576