Rescue of PFOS-induced human Sertoli cell injury by overexpressing a p-FAK-Y407E phosphomimetic mutant

PFOS induces Sertoli cell injury using testicular cells isolated from rodent testes, but it remains unknown if PFOS has similar effects in humans. Herein, we maintained human Sertoli cells in a mitotically active state in vitro, thus enabling transfection experiments that altered gene expression to...

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Detalles Bibliográficos
Autores principales: Chen, Haiqi, Gao, Ying, Mruk, Dolores D., Xiao, Xiang, John, Constance M., Turek, Paul J., Lui, Wing-yee, Lee, Will M., Silvestrini, Bruno, Cheng, C. Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693862/
https://www.ncbi.nlm.nih.gov/pubmed/29150642
http://dx.doi.org/10.1038/s41598-017-15671-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693862/
https://www.ncbi.nlm.nih.gov/pubmed/29150642
http://dx.doi.org/10.1038/s41598-017-15671-4

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