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A genetic system for targeted mutations to disrupt and restore genes in the obligate bacterium, Ehrlichia chaffeensis

Obligate intracellular bacteria (obligates) belonging to Rickettsiales and Chlamydiales cause diseases in hundreds of millions of people worldwide and in many animal species. Lack of an efficient system for targeted mutagenesis in obligates remains a major impediment in understanding microbial patho...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Wei, Lanjing, Liu, Huitao, Cheng, Chuanmin, Ganta, Roman R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693922/
https://www.ncbi.nlm.nih.gov/pubmed/29150636
http://dx.doi.org/10.1038/s41598-017-16023-y