Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity

Oligomannose-type glycans are among the major targets on the gp120 component of the HIV envelope protein (Env) for broadly neutralizing antibodies (bnAbs). However, attempts to elicit oligomannose-specific nAbs by immunizing with natural or synthetic oligomannose have so far not been successful, pos...

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Detalles Bibliográficos
Autores principales: Pantophlet, Ralph, Trattnig, Nino, Murrell, Sasha, Lu, Naiomi, Chau, Dennis, Rempel, Caitlin, Wilson, Ian A., Kosma, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693931/
https://www.ncbi.nlm.nih.gov/pubmed/29150603
http://dx.doi.org/10.1038/s41467-017-01640-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693931/
https://www.ncbi.nlm.nih.gov/pubmed/29150603
http://dx.doi.org/10.1038/s41467-017-01640-y

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