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Axonemal Lumen Dominates Cytosolic Protein Diffusion inside the Primary Cilium

Transport of membrane and cytosolic proteins in primary cilia is thought to depend on intraflagellar transport (IFT) and diffusion. However, the relative contribution and spatial routes of each transport mechanism are largely unknown. Although challenging to decipher, the details of these routes are...

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Detalles Bibliográficos
Autores principales: Luo, Wangxi, Ruba, Andrew, Takao, Daisuke, Zweifel, Ludovit P., Lim, Roderick Y. H., Verhey, Kristen J., Yang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693955/
https://www.ncbi.nlm.nih.gov/pubmed/29150645
http://dx.doi.org/10.1038/s41598-017-16103-z