Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin

Leishmania is a single-celled eukaryotic parasite afflicting millions of humans worldwide, with current therapies limited to a poor selection of drugs that mostly target elements in the parasite’s cell envelope. Here we determined the atomic resolution electron cryo-microscopy (cryo-EM) structure of...

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Detalles Bibliográficos
Autores principales: Shalev-Benami, Moran, Zhang, Yan, Rozenberg, Haim, Nobe, Yuko, Taoka, Masato, Matzov, Donna, Zimmerman, Ella, Bashan, Anat, Isobe, Toshiaki, Jaffe, Charles L., Yonath, Ada, Skiniotis, Georgios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693986/
https://www.ncbi.nlm.nih.gov/pubmed/29150609
http://dx.doi.org/10.1038/s41467-017-01664-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693986/
https://www.ncbi.nlm.nih.gov/pubmed/29150609
http://dx.doi.org/10.1038/s41467-017-01664-4

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