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Atomic resolution snapshot of Leishmania ribosome inhibition by the aminoglycoside paromomycin
Leishmania is a single-celled eukaryotic parasite afflicting millions of humans worldwide, with current therapies limited to a poor selection of drugs that mostly target elements in the parasite’s cell envelope. Here we determined the atomic resolution electron cryo-microscopy (cryo-EM) structure of...
Autores principales: | Shalev-Benami, Moran, Zhang, Yan, Rozenberg, Haim, Nobe, Yuko, Taoka, Masato, Matzov, Donna, Zimmerman, Ella, Bashan, Anat, Isobe, Toshiaki, Jaffe, Charles L., Yonath, Ada, Skiniotis, Georgios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693986/ https://www.ncbi.nlm.nih.gov/pubmed/29150609 http://dx.doi.org/10.1038/s41467-017-01664-4 |
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