Differential regulation of synaptic AP-2/clathrin vesicle uncoating in synaptic plasticity

AP-1/σ1B-deficiency causes X-linked intellectual disability. AP-1/σ1B −/− mice have impaired synaptic vesicle recycling, fewer synaptic vesicles and enhanced endosome maturation mediated by AP-1/σ1A. Despite defects in synaptic vesicle recycling synapses contain two times more endocytic AP-2 clathri...

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Detalles Bibliográficos
Autores principales: Candiello, Ermes, Mishra, Ratnakar, Schmidt, Bernhard, Jahn, Olaf, Schu, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694008/
https://www.ncbi.nlm.nih.gov/pubmed/29150658
http://dx.doi.org/10.1038/s41598-017-16055-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694008/
https://www.ncbi.nlm.nih.gov/pubmed/29150658
http://dx.doi.org/10.1038/s41598-017-16055-4

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