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Ketamine’s antidepressant effect is mediated by energy metabolism and antioxidant defense system

Fewer than 50% of all patients with major depressive disorder (MDD) treated with currently available antidepressants (ADs) show full remission. Moreover, about one third of the patients suffering from MDD does not respond to conventional ADs and develop treatment-resistant depression (TRD). Ketamine...

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Detalles Bibliográficos
Autores principales: Weckmann, Katja, Deery, Michael J., Howard, Julie A., Feret, Renata, Asara, John M., Dethloff, Frederik, Filiou, Michaela D., Iannace, Jamie, Labermaier, Christiana, Maccarrone, Giuseppina, Webhofer, Christian, Teplytska, Larysa, Lilley, Kathryn, Müller, Marianne B., Turck, Christoph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694011/
https://www.ncbi.nlm.nih.gov/pubmed/29150633
http://dx.doi.org/10.1038/s41598-017-16183-x