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Impact of Etoposide on BRCA1 Expression in Various Breast Cancer Cell Lines

Breast cancer 1 (BRCA1), as a tumor suppressor, exerts an effective influence on protecting DNA integrity to suppress the development of breast cancer (BC). BRCA1 expression is induced in response to DNA-damaging agents such as etoposide. Germline BRCA1 gene mutations are associated with development...

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Detalles Bibliográficos
Autores principales: Zhang, Xi, Hofmann, Simone, Harbeck, Nadia, Jeschke, Udo, Sixou, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694421/
https://www.ncbi.nlm.nih.gov/pubmed/28879638
http://dx.doi.org/10.1007/s40268-017-0208-6