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Impact of Etoposide on BRCA1 Expression in Various Breast Cancer Cell Lines
Breast cancer 1 (BRCA1), as a tumor suppressor, exerts an effective influence on protecting DNA integrity to suppress the development of breast cancer (BC). BRCA1 expression is induced in response to DNA-damaging agents such as etoposide. Germline BRCA1 gene mutations are associated with development...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694421/ https://www.ncbi.nlm.nih.gov/pubmed/28879638 http://dx.doi.org/10.1007/s40268-017-0208-6 |