Pharmacokinetics of a New Oral Vitamin D Receptor Activator (2-Methylene-19-Nor-(20S)-1α,25-Dihydroxyvitamin D(3)) in Patients with Chronic Kidney Disease and Secondary Hyperparathyroidism on Hemodialysis

BACKGROUND: 2-Methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D(3) (DP001 or 2MD) is a novel, potent 1α-hydroxylated vitamin D analog that binds to the vitamin D receptor and suppresses parathyroid hormone synthesis and secretion with potential for an improved safety profile compared to existing activ...

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Detalles Bibliográficos
Autores principales: Pandey, Richa, Zella, Julia B., Zhu, Jinge G., Plum, Lori A., Clagett-Dame, Margaret, Blaser, William J., Bedale, Wendy, DeLuca, Hector F., Coyne, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694423/
https://www.ncbi.nlm.nih.gov/pubmed/28905271
http://dx.doi.org/10.1007/s40268-017-0210-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694423/
https://www.ncbi.nlm.nih.gov/pubmed/28905271
http://dx.doi.org/10.1007/s40268-017-0210-z

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